The Isoko may refer to:
Isoko Region: A region located in Delta State, Nigeria. It serves as the traditional homeland for the Isoko people.
Isoko People: An ethnic group indigenous to the Isoko region in Delta State. Known for their rich cultural heritage, the Isoko people play a prominent role in the social and economic landscape of Delta State.
Isoko Language: The native language spoken by the Isoko people. It is an important part of their identity and is widely used in cultural and social gatherings within the Isoko communities.